Are you considering switching from a weekly GLP-1 injection to the new GLP-1 pill? The convenience of no refrigeration or injections may be tempting, but is it truly a better option? Experts weigh in on the common questions surrounding this switch and compare the pill to injections.
Featured Experts
- Dr. Spencer Nadolsky, an obesity and lipid specialist in Portage, MI
- Dr. Melynda Barnes, a board-certified facial plastic surgeon and obesity medicine specialist in New York, and chief medical officer at Ro
Who Is a Good Candidate for the GLP-1 Pill?
According to Dr. Spencer Nadolsky, if you qualify for a GLP-1 injection like Wegovy, you likely qualify for the pill as well. Dr. Melynda Barnes also agrees, stating that the pill is more about preference for those who want the benefits of GLP-1 medication without injections.
How the Pill Compares to Weekly Injections
Dr. Barnes explains that the effectiveness of the Wegovy pill is comparable to injectable GLP-1 medications based on clinical trials. Dr. Nadolsky notes that the oral version provides similar weight loss and side effects to injections.
Reasons People May Want to Switch
To Avoid Needles
For some patients, the convenience of avoiding needles and not needing refrigeration makes the pill a preferred option.
To Minimize After-Shot Side Effects
While side effects are similar, some patients find the daily dosing of the pill to be better tolerated than weekly injections.
To Stay on Maintenance Long Term
Dr. Barnes suggests that the pill can be a more sustainable option for long-term treatment after reaching goal weight.
What to Know Before Switching
Proper timing and consistency are crucial when taking the oral GLP-1 pill for optimal absorption. Dr. Nadolsky emphasizes the importance of following specific instructions for best results.

