Recently, I’ve noticed that my skin has been lacking its usual radiance, the kind of dullness that even a good night’s sleep and some extra water can’t seem to fix on their own. That’s when I decided to try out Kiehl’s brand-new 1cc CollaShot Plumping Serum ($78) along with their popular Micro-Dose Anti-Aging Retinol Serum ($95), combining a plumping serum with a retinol serum to enhance my skincare routine.
In the following sections, I delve into the individual benefits of each serum and how using them together has transformed my approach to layering skincare products.
Exploring the Advantages of Layering Collagen and Retinol
The CollaShot serum is the newer addition, instantly catching the eye with its vibrant pink gel formula infused with vitamin B12. Beyond its striking color, the serum boasts recombinant collagen polypeptides in a cutting-edge supra-liposomal delivery system, designed to penetrate up to 10 layers deep into the skin’s surface. Clinical studies over an eight-week period revealed a 22% improvement in cheek sagging among participants using GLP-1 for weight loss, with 93% reporting visibly plumper skin. Its lightweight, watery consistency absorbs rapidly into the skin.
On the other hand, the Micro-Dose Retinol Serum is a potent yet gentle formula. Featuring pure retinol at a daily-strength micro-dose, along with peptides and ceramides to soothe the skin barrier, this serum is suitable for retinol beginners and those with sensitive skin. According to Kiehl’s global scientific director, Nancy Ilaya, PhD, the precise retinol dosage ensures effective delivery into the skin without causing excessive cell turnover or compromising the skin barrier. A 12-week evaluation by Kiehl’s demonstrated reduced fine lines and wrinkles in 100% of users, with 90% experiencing enhanced firmness.

When used consecutively, this layering technique aligns with dermatologists’ recommendations for skincare application. The plumping CollaShot serum addresses volume and immediate bounce, while the retinol serum focuses on texture and cell turnover over time—complementing each other’s effects. Together, they provide comprehensive skincare benefits, particularly for individuals dealing with collagen and volume changes associated with rapid weight loss.
As GLP-1 treatments become more prevalent, dermatologists observe corresponding changes in skin appearance. Rapid fat loss can lead to reduced facial support due to the interplay of fat and the skin’s collagen network. This explains the surge in popularity of collagen-centric formulations like the ones discussed here. While a serum alone cannot replace lost structural elements, collagen-focused products offer valuable support for skin grappling with dullness and diminished elasticity, irrespective of the underlying cause.

Final Verdict
Since incorporating these two products into my skincare routine, I’ve noticed a significant improvement in the overall vibrancy of my skin—a testament to their effectiveness. Rather than seeking dramatic transformations, I prioritize consistent daily enhancements, which CollaShot and the Micro-Dose Retinol Serum have successfully delivered. As a result, they have become essential staples in my daily regimen.

