When it comes to retinol products, RoC’s lineup continues to shine with visible results. This drugstore favorite has a loyal following for its ability to smooth, firm, and reduce deep wrinkles overnight.
In a recent survey of over 400 NewBeauty readers,* RoC retinol was named as a holy-grail skin-care product by many. One 60-year-old respondent praised its effectiveness on wrinkles, while a 56-year-old shared how it helps reduce wrinkles. Our top pick: RoC Retinol Correxion Anti-Aging + Firming Night Face Moisturizer ($30).
Clinically proven to reduce deep wrinkles by up to 50 percent in 12 weeks, this formula combines pure RoC Retinol with an exclusive mineral complex for enhanced hydration and efficacy. Dermatologist-tested, non-comedogenic, and gentle enough for nightly use, it’s perfect for those looking to introduce retinol into their routine without irritation.

Users have reported immediate hydration, increased radiance in four weeks, and visible wrinkle reduction in just eight weeks. By week twelve, an impressive 93 percent experienced improvement in deep wrinkles, making this one of the most effective over-the-counter retinol moisturizers available. If you’re ready to enhance your nighttime routine, this best-seller could be the solution your skin needs.
*Source: BeautyEngine Advanced Research, 2025