Oprah Winfrey’s journey with GLP-1 medications for weight loss has been widely covered in the media. In 2023, she joined other celebrities in using these drugs for managing weight. While initially facing criticism for this decision, a recent revelation about her relationship with alcohol has been met with a more positive response.
In an exclusive interview with People, Winfrey shared that the medication not only curbs her appetite but also reduces her craving for alcohol. She mentioned being a fan of tequila in the past, even indulging in excessive drinking, but now, thanks to the GLP-1 medication, she has not had a drink in years.
Throughout her career, Winfrey has been open about her struggles with weight, which has resonated with many. In her new book co-authored with obesity expert Dr. Ania M. Jastreboff, she continues this transparency by detailing her experience with GLP-1 medications.
During the interview, Winfrey shared personal details such as her injection routine, side effects, and how she manages them through a healthy lifestyle. She realized the importance of long-term commitment to the medication after stopping it for a year.
For Winfrey, the GLP-1 medication serves as a tool to control overeating messages to the brain and has prompted her to make broader lifestyle changes, including reducing alcohol intake and committing to regular exercise. She expressed feeling more alive and vibrant than ever before, attributing it to a shift from self-blame to self-acceptance.
Despite facing tabloid scrutiny over her weight, Winfrey is now reclaiming her narrative and celebrating her newfound sense of liberation and health. She acknowledges the struggles she went through publicly and expresses gratitude for reaching a healthier state.

